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Vitamin D has recently been discovered to regulate cellular proliferation and differentiation in a variety of tissues, including the skin. Indeed, >150 genes have now been identified as having a direct or indirect effect on skin color. Melanin is produced by cells called melanocytes in the skin and is the primary determinant of skin color in people with darker skin. Many factors influence the color of people’s skin, but the pigment melanin is by far the most important.

Human skin has a wide range of tones and colors, which can be seen in a wide range of demographic populations. Background: In the world scientific tradition, skin color is the primary physical characteristic used to divide humans into groups.